Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT07122466

Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy

Sponsor: Northwell Health

View on ClinicalTrials.gov

Summary

This is a study that aims to understand whether a blood test measuring tumor DNA circulating in the bloodstream (circulating tumor DNA; ctDNA) shows a similar response as observed by a follow-up CT scan. To study this question, ctDNA will be measured at the same times as CT scans (just before the start of treatment, as well as 2 months after), and the response measured by the ctDNA change will be compared to the response seen on the changes between the CT scans. The goal is to make sure that ctDNA response correlates well with CT scan response measurement.

Official title: Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy in Patients With Advanced Pancreatic Cancer: a Prospective, Observational Pilot Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

24

Start Date

2023-05-22

Completion Date

2025-09

Last Updated

2025-08-14

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Tumor DNA circulating in the bloodstream (circulating tumor DNA; ctDNA)

ctDNA will be measured at the same times as CT scans (just before the start of treatment, as well as 2 months after), and the response measured by the ctDNA change will be compared to the response seen on the changes between the CT scans. The goal is to make sure that ctDNA response correlates well with CT scan response measurement.

Locations (1)

Zuckerberg Cancer Center

New Hyde Park, New York, United States