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Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy
Sponsor: Northwell Health
Summary
This is a study that aims to understand whether a blood test measuring tumor DNA circulating in the bloodstream (circulating tumor DNA; ctDNA) shows a similar response as observed by a follow-up CT scan. To study this question, ctDNA will be measured at the same times as CT scans (just before the start of treatment, as well as 2 months after), and the response measured by the ctDNA change will be compared to the response seen on the changes between the CT scans. The goal is to make sure that ctDNA response correlates well with CT scan response measurement.
Official title: Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy in Patients With Advanced Pancreatic Cancer: a Prospective, Observational Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
24
Start Date
2023-05-22
Completion Date
2025-09
Last Updated
2025-08-14
Healthy Volunteers
No
Conditions
Interventions
Tumor DNA circulating in the bloodstream (circulating tumor DNA; ctDNA)
ctDNA will be measured at the same times as CT scans (just before the start of treatment, as well as 2 months after), and the response measured by the ctDNA change will be compared to the response seen on the changes between the CT scans. The goal is to make sure that ctDNA response correlates well with CT scan response measurement.
Locations (1)
Zuckerberg Cancer Center
New Hyde Park, New York, United States