Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
Sponsor: Kocaeli City Hospital
Summary
This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated. Patients managed with three different anesthesia methods currently used will be examined for recovery patterns: 1. Total intravenous anesthesia (TIVA), 2. TIVA Combined anesthesia with sevoflurane and intravenous agents (sevoflurane-CIVIA), 3. TIVA Combined anesthesia with desflurane and intravenous agents (desflurane-CIVIA). Recovery patterns include; extubation time, eye opening time, emergence agitation, postoperative nausia and vomiting and postoperative recovery unit discharge time.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
210
Start Date
2025-07-23
Completion Date
2025-11-15
Last Updated
2025-08-14
Healthy Volunteers
Yes
Interventions
Sevofluorane
In this group of patients, \<0.5 MAC sevoflurane will be used in combination with TIVA. (TIVA method described above)
Desflurane
In this group of patients, \<0.5 MAC Desflurane will be used in combination with TIVA.
Total Intravenous Anesthesia(TIVA)
In this group, TIVA will be applied with the combination of BIS-guided propofol + remifentanil.
Locations (1)
Kocaeli City Hospital
Kocaeli, Izmıt, Turkey (Türkiye)