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The Correlation Between Red Cell Transfusion and Complications of Prematurity
Sponsor: Clinical Hospital Center Rijeka
Summary
The aim of this clinical trial is to learn if there is a correlation between the erythrocyte transfusion in the early neonatal period in premature infants and early and late complications of prematurity. The main questions it aims to answer are: * Do premature infants who receive blood transfusions within their first month of life have a higher risk of early prematurity complications, such as retinopathy of prematurity, necrotising enterocolitis, bronchopulmonary dysplasia, and intraventricular haemorrhage? * Do premature infants who receive blood transfusions during their first month of life have worse neurological and neurodevelopmental outcomes than those who do not? The first part of the study is retrospective, using data collected from participants' histories. The second part is prospective, evaluating neurological and neurodevelopmental outcomes at the age of six years.
Official title: The Correlation Between Packed Red Blood Cell Transfusion and Early and Late Complications of Prematurity
Key Details
Gender
All
Age Range
6 Years - 7 Years
Study Type
OBSERVATIONAL
Enrollment
128
Start Date
2025-09-01
Completion Date
2029-03-01
Last Updated
2025-08-14
Healthy Volunteers
No
Conditions
Interventions
Wechsler Intelligence Test, performed by educated psychologists
At the age of six, parents of children who meet the inclusion criteria will receive a notification about the study from the responsible paediatrician. If they agree to participate, they will sign an informed consent form. They will then be invited to the clinic for a neurological and neurodevelopmental assessment. The neurological examination will be conducted by the principal investigator or collaborators who are paediatric specialists. The neurodevelopmental evaluation will be performed by a qualified psychologist using the Wechsler Intelligence Test. The Wechsler Intelligence Test for Children - Fourth Edition is a clinical tool for measuring the intelligence of children aged 6 to 16 years and 11 months. It assists in identifying specific learning difficulties, hyperactivity disorder, speech and language challenges, and intellectual impairments. The test comprises 15 subtests.
Locations (1)
Clinical Hospital Centre Rijeka, Department of Paediatrics
Rijeka, Primorje-Gorski Kotar County, Croatia