Inclusion Criteria:
* Diagnosis of focal epilepsy as documented in the medical record.
* Implanted at least 1 year ago with RNS.
* RNS device actively recording intracranial EEG data.
* Baseline RNS recordings show that the over 50% of detections represent epileptiform seizure onset patterns.
* Provision of signed and dated informed consent form.
* Ability to take oral medication and be willing to adhere to the BHV-7000 treatment regimen.
* Body mass index (BMI) \< 40 kg/m² at screening visit.
Exclusion Criteria:
* Change in any antiseizure medication (including addition or discontinuation of any antiseizure
* Any change in RNS detection settings within 90 days prior to planned treatment Day 1.
* Change in RNS stimulation settings within 90 days prior to planned drug administration (retrospective baseline period).
* Poor or inconsistent history of device downloads in the 90 days prior to planned treatment Day 1, as determined by less than 90% of episode start data being available at treatment Day 1.
* RNS battery low (estimated to last for less than 3 months).
* Schizophrenia and other psychotic disorders (e.g., schizophreniform disorder, schizoaffective disorder, psychosis not otherwise specified \[NOS\]), bipolar disorder, and/or obsessive-compulsive disorder, or other serious mental health disorders. Uncontrolled unipolar major depression where changes in pharmacotherapy are needed or anticipated during the study.
* Active suicidal plan/intent in the past six months, a suicide attempt in the last two years, or more than one lifetime suicide attempt.
* History of illicit drug or alcohol abuse within one year prior to screening judged by the PI to be excessive or compulsive, or currently using drugs of abuse or any prescribed or over the counter medication in a manner that the PI considers indicative of abuse or dependence.
* History of cancer within the past two years, with the exception of appropriately treated basal cell or squamous cell carcinoma.
* History of clinically significant urinary retention in the judgment of the PI.
* Previous exposure to BHV-7000 or known allergy to BHV-7000 or its excipients.
* Any major surgery within one month or an acute illness within two weeks prior to screening.
* Vaccination within the previous four weeks prior to screening or planned vaccination during the study.
* History of ezogabine use.
* Known allergic reactions to components of the study drug.
* Febrile illness within 90 days prior to planned treatment Day 1.
* Significant cardiovascular history, including but not limited to uncontrolled angina, myocardial infarction (Ml) within 12 months of screening, clinically significant arrhythmia, congestive heart failure (New York Heart Association \[NYHA\] Class Ill or higher).
* QTcF (Fridericia) interval 450 msec for males and 470 msec for females; Mobitz Type II second or third degree atrioventricular (AV) block, or complete left bundle branch block, or complete right bundle branch block, or intraventricular conduction defect with a QRS duration 130 msec, or evidence of acute or sub-acute myocardial infarction (Ml) or ischemia, or other ECG findings that, in the investigator's opinion, would preclude participation in the study.
