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Serological Responses to Adjuvanted Versus Non-adjuvanted Influenza Vaccines Among People With HIV: a Randomized Clinical Trial
Sponsor: National Taiwan University Hospital
Summary
Until now, the adjuvanted influenza-related studies focused mainly on people at older ages. However, the data on immunocompromised people, who might have suboptimal serological responses when receiving nonadjuvanted vaccines, is scarce. In this study, we aim to compare the immunogenicity and safety to adjuvanted versus nonadjuvanted seasonal influenza vaccines among people with HIV.
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2025-10-01
Completion Date
2027-12-31
Last Updated
2025-08-17
Healthy Volunteers
No
Conditions
Interventions
MF-59
MF-59 influenza vaccination
cell-based
cell-based influenza vaccination
egg-based
egg-based influenza vaccination