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Study on the Mechanism of Zuoqing San Promoting Postoperative Wound Healing of Anal Fistula by Inhibiting ROS-dependent NETosis
Sponsor: The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Summary
This study adopted a randomized, double-blind, placebo-controlled clinical trial design to evaluate the efficacy and safety of Zuoqing San fumigation and washing on the wound healing after anal fistula surgery.
Official title: The First Affiliated Hospital of Anhui University of Chinese Medicine
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-08-01
Completion Date
2026-02-01
Last Updated
2025-08-19
Healthy Volunteers
No
Conditions
Interventions
Solution of Zuoqing San for fumigation and washing of the postoperative wound of anal fistula
Left Qing San Decoction (25g of Cai Yin + 30g of Eucommia + 25g of Sophora flavescens + 25g of Anemarrhena asphodeloides + 15g of Lithospermum erythrorhizon, prepared in the Pharmacy Department of Anhui University of Traditional Chinese Medicine), add 1000mL of water, boil, then steam and wash the wound surface. The temperature is 40 ± 2℃. Do it once a day, for 15 minutes each time, for 7 consecutive days.
Equal-volume placebo inhalation rinse
Equal-volume placebo inhalation rinse
Locations (1)
Anhui university of Chinese Medicine
Hefei, Anhui, China