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ENROLLING BY INVITATION
NCT07128953
EARLY_PHASE1

Study on the Mechanism of Zuoqing San Promoting Postoperative Wound Healing of Anal Fistula by Inhibiting ROS-dependent NETosis

Sponsor: The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine

View on ClinicalTrials.gov

Summary

This study adopted a randomized, double-blind, placebo-controlled clinical trial design to evaluate the efficacy and safety of Zuoqing San fumigation and washing on the wound healing after anal fistula surgery.

Official title: The First Affiliated Hospital of Anhui University of Chinese Medicine

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-08-01

Completion Date

2026-02-01

Last Updated

2025-08-19

Healthy Volunteers

No

Conditions

Interventions

DRUG

Solution of Zuoqing San for fumigation and washing of the postoperative wound of anal fistula

Left Qing San Decoction (25g of Cai Yin + 30g of Eucommia + 25g of Sophora flavescens + 25g of Anemarrhena asphodeloides + 15g of Lithospermum erythrorhizon, prepared in the Pharmacy Department of Anhui University of Traditional Chinese Medicine), add 1000mL of water, boil, then steam and wash the wound surface. The temperature is 40 ± 2℃. Do it once a day, for 15 minutes each time, for 7 consecutive days.

OTHER

Equal-volume placebo inhalation rinse

Equal-volume placebo inhalation rinse

Locations (1)

Anhui university of Chinese Medicine

Hefei, Anhui, China