Clinical Research Directory

Inclusion Criteria: * Age: 18 years old or older and under 45 years old. * Patients with anterior cruciate ligament injury who are candidates for reconstruction surgery. Exclusion Criteria: * Chronic anterior cruciate ligament injury (injury occurred more than 12 months ago). * History of knee surgery, including anterior cruciate ligament surgery on the index side. * Complication or history cruciate ligament injury on the opposite side, history of total knee arthroplasty, osteotomy around the knee, or osteosynthesis around the knee on the opposite side. * Meniscus injury that requires extensive resection and is impossible to suture on the index side, collateral ligament injury or posterior cruciate ligament injury of 2° or more on the index side. * Complication of osteoarthritis of the knee on the index side, KL classification 2° or higher. * Complications of cartilage damage that cannot be treated by drilling or microfracture on the index side. * Patients with infection in the index knee or inflammatory joint disease such as rheumatoid arthritis. * Patients undergoing radiation therapy, chemotherapy, or both. * Patients currently receiving treatment with systemic steroids, immunosuppressants, or both. * Patients who are allergic to bovine products (e.g. meat). * Patients who cannot discontinue returning to sports until 9 months after reconstruction surgery. * Pregnant, breastfeeding and possibly pregnant patients. * Female patients of childbearing potential and male patients who cannot agree to contraception for at least one year after reconstruction surgery. * Patients who participated in other clinical trials within 4 weeks prior to reconstruction surgery.