Clinical Research Directory

Inclusion Criteria: 1. Age: 18-80 years, 2. Ability to comprehend and provide written informed consent. Exclusion Criteria: 1. Comorbid severe conditions (e.g., recent acute myocardial infarction, unstable angina, uncontrolled arrhythmias, severe aortic coarctation or descending aortic aneurysm, acute myocarditis or pericarditis, acute congestive heart failure, acute respiratory failure, resting oxygen saturation \<93%, recent arterial or pulmonary embolism, pulmonary edema). 2. Conditions potentially exacerbated by exercise (e.g., acute cardiac insufficiency, exercise-induced asthma, epilepsy). 3. Physical disability due to musculoskeletal or neuromuscular disorders. 4. Pregnancy or lactation. 5. Patients deemed unsuitable for participation by the investigator.