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Sirolimus Discontinuation Strategies in Kaposiform Hemangioendothelioma
Sponsor: West China Hospital
Summary
Sirolimus has demonstrated efficacy in the treatment of kaposiform hemangioendothelioma (KHE); however, a high rate of rebound growth following discontinuation has been reported, highlighting the clinical importance of establishing an appropriate withdrawal regimen.
Official title: A Randomized Controlled Trial Comparing Three Sirolimus Discontinuation Strategies in Patients With Kaposiform Hemangioendothelioma
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-09-13
Completion Date
2028-02-01
Last Updated
2025-09-08
Healthy Volunteers
No
Conditions
Interventions
Sirolimus
Comparison of different sirolimus discontinuation strategies.
Locations (1)
West China Hospital of Sichuan University
Chengdu, Sichuan, China