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RECRUITING
NCT07135037
PHASE2

Comparison Between Treatments of Oligohydramnios

Sponsor: Kafrelsheikh University

View on ClinicalTrials.gov

Summary

Based on previous studies, Both sildenafil and L-arginine helped to improve idiopathic oligohydramnios. In this study, Level of improvment of oligohydramnios will be compared. As well as, NICU admission to neonates of pregnancies complicated by idiopathic oligohydramnios. The end goal is to help physicians use the best drug for their patients.

Official title: Efficacy of L- Arginine Versus Sildenafil in Management of Idiopathic Oligohydramnios

Key Details

Gender

FEMALE

Age Range

18 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-09-01

Completion Date

2025-12-31

Last Updated

2025-08-21

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Sildenafil 25 MG

Sildenafil is a vasodilator drug which improve blood supply to placenta.Therefore, it should improve idiopathic oligohydramnios.

DRUG

L-Arginine, 1000 Mg Oral Tablet

Aminoacid with vasodilator property which improve blood supply to placenta.Therefore, it should improve idiopathic oligohydramnios.

Locations (2)

Kafrelsheikh University Hospital

Kafr ash Shaykh, Kafrelsheikh, Egypt

Kafrelsheokh university hospital

Kafr ash Shaykh, Kafrelsheikh, Egypt