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Incidence of Postoperative Cognitive Decline in Patients With Preexisting Cognitive Impairment
Sponsor: Peking University Shenzhen Hospital
Summary
This study aims to find out how often memory and thinking problems happen after surgery in people who already have memory issues before their operation. These memory problems are called postoperative cognitive decline (POCD). Older adults with memory problems before surgery may be more likely to have trouble with thinking, memory, and daily activities after their operation. This study will follow patients who already have memory problems before surgery and see how their thinking and memory change after surgery. The results will help doctors better understand how to care for these patients before, during, and after surgery.
Official title: Incidence of Postoperative Cognitive Decline in Surgical Patients With Preexisting Cognitive Impairment: A Prospective Cohort Study
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
OBSERVATIONAL
Enrollment
340
Start Date
2025-07-15
Completion Date
2027-07-01
Last Updated
2025-08-22
Healthy Volunteers
Yes
Conditions
Interventions
surgery
Patients with preexisting cognitive impairment undergoing elective non-cardiac surgery under general anesthesia.
norma
Cognitively normal individuals who do not undergo surgery but complete the same cognitive assessments at baseline, 3 months, and 12 months for normative reference.
Locations (1)
Peking University Shenzhen Hospital
Shenzhen, Guangdong, China