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RECRUITING
NCT07140211
PHASE3

Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis

Sponsor: Marc Blondon

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to evaluate the risk-benefit of a short-term treatment with a low-dose low-molecular-weight heparin (LMWH), in the postpartum period (after delivery). The main questions it aims to answer are: * compared to no treatment, does short-term postpartum LMWH modify the risk of venous thromboembolism within 90 days of delivery? * compared to no treatment, does short-term postpartum LMWH modify the risks of bleeding and wound complications? Participants will take low-dose LMWH for 7-10 days or no treatment, and will be followed for 90 days post-delivery.

Official title: Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis: a Pragmatic, Multi-center, Open-label Randomized Controlled Study

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

9200

Start Date

2025-10-15

Completion Date

2030-08

Last Updated

2026-02-17

Healthy Volunteers

No

Interventions

DRUG

Low-dose low-molecular-weight heparin

Low-molecular-weight heparin given for 7-10 days after delivery: * enoxaparin 4000-6000IU o.d. * nadroparin 3800-5700IU o.d. * dalteparin 5000-7500IU o.d. * tinzaparin 4500-7000IU o.d.

Locations (1)

Geneva University Hospitals

Geneva, Switzerland