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The Effect of Oral Oxytocin and Atosiban on Top-down Attention ( OTAtosiban )
Sponsor: University of Electronic Science and Technology of China
Summary
The main aim of the present study is to investigate whether orally (lingual spray) administered oxytocin influences human top-down attention via oxytocin receptors and whether its effects are dose- and task-dependent.
Official title: The Influence and Regulatory Role of Exogenous and Endogenous Oxytocin on Top-down Attention in Humans
Key Details
Gender
MALE
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
250
Start Date
2025-09
Completion Date
2025-12-30
Last Updated
2025-09-08
Healthy Volunteers
Yes
Conditions
Interventions
Oxytocin lower does (24IU)
Oxytocin (24IU) will be administered as a lingual spray (6, 0.1puffs (4IU per puff) of spray on and under the tongue)
Oxytocin higher does (48IU)
Oxytocin (48IU) will be administered as a lingual spray (6, 0.1ml sprays (8IU per puff) on and under the tongue)
Atosiban
150ug atosiban administered by lingual sprays (6, 0.1ml sprays on and under the tongue)
Placebo
Placebo administered as a lingual spray (6, 0.1puffs (4IU per puff) of spray on and under the tongue). Placebo has the same composition of 0.9% saline and glycerol as for oxytocin and the atosiban interventions.
Locations (1)
School of Life science and Technology, University of Electronic Science and Technology of China
Chengdu, Sichuan, China