Clinical Research Directory

Inclusion Criteria: 1. Diagnosed with Crawford type III-IV thoracoabdominal aortic aneurysm or complex abdominal aortic aneurysm, with a healthy proximal landing zone (\>20mm length, angulation \<60°) in the descending aorta and maximum aneurysm diameter ≥4cm 2. Scheduled for endovascular aortic repair with commercially available iliac branch devices for visceral artery reconstruction 3. Signed informed consent and committed to protocol-defined follow-up Exclusion Criteria: 1. Acquired language barrier, intellectual decline, cognitive impairment, or mental illness preventing informed consent 2. Uncontrolled autoimmune diseases (e.g., Takayasu arteritis, systemic lupus erythematosus, vasculitis) 3. Prior aortic surgery with stent-graft or prosthetic vascular graft implantation 4. End-stage renal/hepatic/cardiac/pulmonary failure or malignancy diagnosed within 5 years, likely to cause mortality during follow-up 5. Active bleeding or coagulopathy within 6 months (high bleeding risk) 6. Uncontrolled hypertension (resting SBP \>180 mmHg or DBP \>110 mmHg) 7. Uncontrolled diabetes (fasting blood glucose \>16.7 mmol/L) 8. Severe hepatic/renal dysfunction (serum creatinine \>3 mg/dL, ALT/AST \>3×ULN) 9. Concurrent participation in other interventional clinical trials 10. Pregnancy or perinatal status 11. Refusal to sign informed consent