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RECRUITING
NCT07142707
PHASE1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

Sponsor: MBX Biosciences

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the safety and tolerability of single and multiple subcutaneous (SC) doses of MBX 4291 in adults with obesity.

Official title: A Randomized, Double-blind, Placebo-controlled First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of MBX 4291 in Adult Participants With Obesity

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

64

Start Date

2025-09-03

Completion Date

2026-05-30

Last Updated

2025-12-15

Healthy Volunteers

No

Conditions

Interventions

DRUG

MBX 4291

MBX 4291 will be administered subcutaneously (SC)

DRUG

Placebo

Placebo: Placebo will be administered subcutaneously (SC)

Locations (1)

MBX Biosciences Investigational Site

Knoxville, Tennessee, United States