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Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry
Sponsor: Biocells Medical
Summary
This retrospective observational study will analyze de-identified clinical data from patients with amyotrophic lateral sclerosis (ALS) collected at multiple centers over 7 years. The primary objective is to describe disease progression using the ALS Functional Rating Scale-Revised (ALSFRS-R). Secondary objectives include evaluating survival, ventilatory decline, and correlations between available biomarkers (e.g., neurofilament light chain, cytokines) and disease trajectory. No new interventions or patient contact will occur.
Official title: Natural History and Biomarker Correlation Study in Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
36
Start Date
2021-05-13
Completion Date
2028-09-01
Last Updated
2025-08-28
Healthy Volunteers
No
Conditions
Interventions
Imaging and Clinical Reports
Inclusion of existing imaging data (MRI, EMG reports) and standard clinical documentation, where available.
Locations (1)
Biocells Medical
Warsaw, Poland