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RECRUITING
NCT07143695
NA

Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion

Sponsor: Cairo University

View on ClinicalTrials.gov

Summary

Increased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely evaluated. There is growing evidence concerning respiratory muscles dysfunction that contributes to difficulty or prolonged liberation from MV.

Official title: Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion to Minimize Re-intubation Rate: a Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2025-09-01

Completion Date

2026-08-31

Last Updated

2025-09-08

Healthy Volunteers

No

Conditions

Interventions

DEVICE

Parasternal intercostal thickening fraction

Parasternal intercostal thickening fraction less than 6.5%

DEVICE

Sham parasternal intercostal thickening

Ultrasound assessment only for purpose of blinding

Locations (1)

Cairo University

Cairo, Giza Governorate, Egypt