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Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion
Sponsor: Cairo University
Summary
Increased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely evaluated. There is growing evidence concerning respiratory muscles dysfunction that contributes to difficulty or prolonged liberation from MV.
Official title: Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion to Minimize Re-intubation Rate: a Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2025-09-01
Completion Date
2026-08-31
Last Updated
2025-09-08
Healthy Volunteers
No
Conditions
Interventions
Parasternal intercostal thickening fraction
Parasternal intercostal thickening fraction less than 6.5%
Sham parasternal intercostal thickening
Ultrasound assessment only for purpose of blinding
Locations (1)
Cairo University
Cairo, Giza Governorate, Egypt