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Transcranial Pulse Stimulation for Alzheimer's Disease
Sponsor: Chinese University of Hong Kong
Summary
TPS is a non-invasive therapeutic modality that uses focused, low-energy pulse stimulation to stimulate tissue regeneration and reduce inflammation. In the context of neurological disorders, it is hypothesized that TPS can modulate neuronal activity, enhance synaptic plasticity, and reduce neuroinflammation. It is a relatively new application in neurological disease treatment and is still under intense investigation.
Official title: A Pilot Randomized Placebo-Controlled Trial of Transcranial Pulse Stimulation (TPS) in Early Alzheimer's Disease (AD) Subjects
Key Details
Gender
All
Age Range
60 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-07-21
Completion Date
2026-06
Last Updated
2025-09-16
Healthy Volunteers
No
Conditions
Interventions
transcranial pulse stimulation (TPS)
The TPS/Sham-TPS therapy is administered for the first two weeks, followed by additional sessions at some week intervals.
transcranial pulse stimulation (TPS-Sham)
Participants will undergo an identical procedure using a device that mimics the sound and sensation of active TPS but delivers no therapeutic energy pulses to the brain.
Locations (1)
Department of Medicine & Therapeutics, Faculty of Medicine, The Chinese UNiversity of Hong Kong
Hong Kong, Hong Kong