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Enhancing Slow Wave Sleep in Depression
Sponsor: Wake Forest University Health Sciences
Summary
The goal of this pilot study is to determine if non-invasive brain stimulation during sleep can increase deep sleep in adults with depression. It will also determine if increased deep sleep improves cognitive performance and mood ratings. Participants will be asked to wear a non-invasive device that records their brain activity and delivers transcranial electrical stimulation during sleep. Participants will also wear an actigraphy watch that measures activity levels throughout the study. In addition, participants will complete several cognitive assessments and mood and sleep questionnaires throughout the study.
Official title: Investigating Slow Wave Sleep Enhancement to Improve Cognitive Function in Adults With Depression
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2026-04
Completion Date
2026-12
Last Updated
2026-03-27
Healthy Volunteers
No
Conditions
Interventions
Transcranial Electrical Stimulation (TES)
Using the Sleep WISP device, transcranial electrical stimulation will be delivered during sleep as 0.5 Hz sine wave, 0.5 mA, between frontal (frontopolar and inferior lateral frontal) and posterior (mastoid and occipital) electrodes.
Locations (1)
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States