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NOT YET RECRUITING
NCT07146802
NA

Personalized Metacognitive Training for Psychosis: A Randomized Controlled Trial

Sponsor: University Hospital, Strasbourg, France

View on ClinicalTrials.gov

Summary

This study aims to compare the efficacy of classical Metacognitive Training (MCT) and personalized Metacognitive Training (P-MCT) for individuals with psychosis. MCT is a psychoeducational program derived from cognitive-behavioral therapy (CBT) that targets cognitive biases associated with psychotic symptoms. The goal is to assess which intervention is more effective to improve the overall functioning of individuals with psychosis. The study will use machine learning to personalize the treatment approach and evaluate its impact on clinical symptoms, cognitive functions, and quality of life.

Official title: Towards a Personalized Medicine Approach to Psychological Treatment for Psychosis

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

51

Start Date

2025-10-01

Completion Date

2027-04-01

Last Updated

2025-09-15

Healthy Volunteers

No

Interventions

BEHAVIORAL

Metacognitive Training (MCT) for psychosis

MCT for psychosis is based on the theoretical foundations of the cognitive-behavioral model of schizophrenia, but it employs a somewhat different therapeutic approach. The program is comprised of ten modules targeting common cognitive errors, problem-solving biases as well as emotional problems in schizophrenia. These errors and biases may, on their own or in combination, culminate in the establishment of false beliefs to the point of delusions. The aim of the sessions is to raise the participants' awareness of these distortions and to prompt them to critically reflect on, expand upon, and change their current repertoire of problem solving. In addition to the sessions, the program includes homework tasks to reinforce the skills learned between sessions.