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RECRUITING
NCT07148154

Development of a Non-invasive IVD for Endometrial Cancer Screening on High-risk Populations

Sponsor: MiMARK Diagnostics, S.L.

View on ClinicalTrials.gov

Summary

CYTOMARK, a non-invasive in vitro diagnostic (IVD) test measuring a defined panel of protein biomarkers in cervical fluid, can accurately detect endometrial cancer in both symptomatic and asymptomatic women at high risk for the disease. The aim of the study consists in validating CYTOMARK's ELISA test, creating and freezing an algorithm detect EC in post-menopausal women with abnormal uterine bleeding (AUB).

Official title: ScreenEC: Development of a Non-invasive IVD for Endometrial Cancer Screening on High-risk Populations

Key Details

Gender

FEMALE

Age Range

40 Years - Any

Study Type

OBSERVATIONAL

Enrollment

3000

Start Date

2024-06-24

Completion Date

2026-09-30

Last Updated

2025-08-29

Healthy Volunteers

Yes

Interventions

DEVICE

Cytology

Two cervical samples are collected using a cervical brush or swab, following the standard procedure for cervical cytology. Cells are taken from the cervix using a brush/spatula during a gynecological exam. (1) The first sample is kept in the clinical center's pathology department for examination. (2) The second sample is sent to MiMARK's facilities for the investigational project, where it will be processed and stored for future cohort selection and analysis.

Locations (2)

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, Barcelona, Spain

Hospital Universitari Campus Vall d'Hebron

Barcelona, Spain