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PET/CT for Trop2 ADC Response Evaluation NSCLC
Sponsor: The First Affiliated Hospital of Xiamen University
Summary
To evaluate whether serial 68Ga-MY6349 PET/CT imaging can serve as a noninvasive biomarker to predict the therapeutic efficacy of Trop2-targeted antibody-drug conjugate (Trop2-ADC) therapy in NSCLC patients.
Official title: Evaluation of Treatment Response to Trop2 ADC by 68Ga-MY6349 PET/CT in NSCLC
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2025-05-01
Completion Date
2027-05-01
Last Updated
2025-09-03
Healthy Volunteers
No
Interventions
68Ga-MY6349 PET/CT
Each participant will receive an intravenous injection of 68Ga-MY6349 and undergo PET/CT imaging at baseline and following two and/or four cycles of Trop2-ADC therapy.
Locations (1)
The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, China