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ENROLLING BY INVITATION
NCT07151963
NA

Effects of Prolonged Continuous Theta Burst Stimulation in Chemotherapy-induced Peripheral Neuropathy

Sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

View on ClinicalTrials.gov

Summary

Laboratory studies have shown that prolonged continuous theta burst stimulation (pcTBS) provides better pain relief than 10 Hz repetitive transcranial magnetic stimulation (rTMS), with a shorter stimulation time, making it more practical for clinical use. Chemotherapy-induced peripheral neuropathy often causes neuropathic pain in cancer patients. The aims of this study are: 1. To compare the effects of pcTBS and 20 Hz rTMS on chemotherapy-induced peripheral neuropathy; 2. To compare the effects of pcTBS applied to the primary motor cortex versus the dorsolateral prefrontal cortex on neuropathic pain as well as depression and anxiety.

Official title: Effects of Prolonged Continuous Theta Burst Stimulation in Chemotherapy-induced Peripheral Neuropathy: a Randomized Cross- Over Trial

Key Details

Gender

FEMALE

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2025-02-17

Completion Date

2027-07-31

Last Updated

2025-09-11

Healthy Volunteers

No

Interventions

DEVICE

prolonged continuous TBS

prolonged continuous theta burst stimulation

DEVICE

20 Hz rTMS

20 Hz repetitive transcranial magnetic stimulation

Locations (1)

Taipei Tzu Chi Hospital

New Taipei City, Taiwan