Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effects of Prolonged Continuous Theta Burst Stimulation in Chemotherapy-induced Peripheral Neuropathy
Sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Summary
Laboratory studies have shown that prolonged continuous theta burst stimulation (pcTBS) provides better pain relief than 10 Hz repetitive transcranial magnetic stimulation (rTMS), with a shorter stimulation time, making it more practical for clinical use. Chemotherapy-induced peripheral neuropathy often causes neuropathic pain in cancer patients. The aims of this study are: 1. To compare the effects of pcTBS and 20 Hz rTMS on chemotherapy-induced peripheral neuropathy; 2. To compare the effects of pcTBS applied to the primary motor cortex versus the dorsolateral prefrontal cortex on neuropathic pain as well as depression and anxiety.
Official title: Effects of Prolonged Continuous Theta Burst Stimulation in Chemotherapy-induced Peripheral Neuropathy: a Randomized Cross- Over Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-02-17
Completion Date
2027-07-31
Last Updated
2025-09-11
Healthy Volunteers
No
Conditions
Interventions
prolonged continuous TBS
prolonged continuous theta burst stimulation
20 Hz rTMS
20 Hz repetitive transcranial magnetic stimulation
Locations (1)
Taipei Tzu Chi Hospital
New Taipei City, Taiwan