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Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
Sponsor: The University of Texas Health Science Center at San Antonio
Summary
After the removal of a tooth, a bone graft is often placed in the socket to try to keep the volume of bone that was there when the tooth was present so that the bone does not "shrink". The bone graft is sometimes kept in place with a small piece of material over the top of the tooth socket and with stitches. This procedure is called "Ridge Preservation". Many different materials are used for ridge preservation including bone allografts (bone grafts derived from a human tissue donor), bone xenografts (bone grafts derived from species other than humans, such as cows and pigs), and synthetic materials that are similar in structure to bone (such as calcium apatite). The bone allograft and the calcium apatite product used in this study are Food and Drug Administration (FDA) approved. This study will compare the two methods used to see how much new bone formation there is inside the tooth socket at about 16 weeks of healing after ridge preservation with a calcium apatite/collagen sponge versus an allograft.
Official title: Wound Healing Following Tooth Extraction and Ridge Preservation Using Resorbable Non-ceramic Calcium Apatite Granules in Type I Bovine Collagen Plugs (OsteoGen®)
Key Details
Gender
All
Age Range
18 Years - 89 Years
Study Type
INTERVENTIONAL
Enrollment
44
Start Date
2025-11-19
Completion Date
2027-12-31
Last Updated
2026-01-06
Healthy Volunteers
Yes
Conditions
Interventions
Combination 70% FDBA and 30% DFDBA
A combination freeze-dried bone allograft consisting of 70% mineralized FDBA and 30% demineralized FDBA
OsteoGen Plug
A synthetic calcium apatite material combined with Type 1 bovine collagen (in a sponge-like product)
Locations (1)
University of Texas Health Science Center at San Antonio School of Dentistry
San Antonio, Texas, United States