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Topical Rifamycin SV for Wound Healing After Sapphire FUE Hair Transplantation
Sponsor: Elif Asena KANTARCI
Summary
This prospective, parallel-group controlled clinical study evaluated whether a single topical rifamycin SV protocol added to standardized care after sapphire follicular unit extraction (FUE) was associated with earlier recorded wound healing. One hundred candidates were assessed, and 70 men were individually allocated 1:1 using MedCalc. Five participants were excluded after allocation but before surgery and before receiving the assigned intervention because final preoperative serological testing met prespecified exclusion criteria. The analyzed sample comprised 34 participants in the rifamycin SV group and 31 in the control group. Healing was assessed through postoperative Day 14 using scheduled clinical review and serial photographs. Infection and hypersensitivity were monitored as safety outcomes.
Official title: Topical Rifamycin SV After Sapphire FUE: Accelerated Wound Healing and Anticipatory and Preventive Nursing Care
Key Details
Gender
MALE
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2021-12-02
Completion Date
2022-06-22
Last Updated
2026-09-15
Healthy Volunteers
No
Conditions
Interventions
Povidone-Iodine 10%
Preoperative skin antisepsis performed with 10% povidone-iodine solution according to standard surgical preparation guidelines before hair transplantation.
Rifamycin SV Sodium
One complete ampule containing rifamycin SV sodium 125 mg/1.5 mL was drawn into a syringe and applied topically and off-label; it was not injected. The clinical nurse-investigator applied 0.75 mL dropwise to the donor surface after graft harvesting and before dressing and 0.75 mL to the recipient surface after graft implantation was completed. Each application was distributed with separately applied normal saline spray.
Locations (1)
Bahcesehir University, School of Health Sciences, Department of Nursing
Istanbul, Besiktas, Turkey (Türkiye)