Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT07155759
NA

Long-term Outcomes of Prostate Cancer Screening

Sponsor: Karolinska Institutet

View on ClinicalTrials.gov

Summary

This study is an expansion of the screening-by-invitation STHLM3MRI trial for detection of prostate cancer. In summary, we assess longterm outcomes (prostate cancer mortality, incidence and resource use) in men (i) invited and randomized to a screening program using PSA, a biomarker test and MRI; (ii) invited and randomized to a single PSA test with prostate biopsies followed by opportunistic testing and (iii) population controls. Mortality is verified through register data, disease verification is made through in-study biopsy results and registry data.

Official title: Long-term Outcomes of Prostate Cancer Screening Using PSA, Biomarkers and MRI: The STHLM3MRI Trial

Key Details

Gender

MALE

Age Range

50 Years - 74 Years

Study Type

INTERVENTIONAL

Enrollment

7500

Start Date

2024-11-01

Completion Date

2035-11

Last Updated

2025-09-04

Healthy Volunteers

Yes

Conditions

Interventions

DIAGNOSTIC_TEST

PSA/Stockholm3/MRI

Stockholm3+PSA followed by MRI of the prostate

DIAGNOSTIC_TEST

PSA

PSA followed by standard biopsies

Locations (1)

Karolinska Institutet

Stockholm, Sweden