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A Study on the Heterogeneity of Efficacy of Interventional Therapy Combined With Systemic Therapy for Liver Cancer Based on Multi-center Real-world Data
Sponsor: Xuhua Duan
Summary
The system assesses the heterogeneity of HCC patients in terms of therapeutic outcomes (such as rwPFS, ORR, PRO) and adverse reactions during the process of interventional therapy combined with systemic treatment. It explores the clinical characteristics and biomarker levels of patients related to heterogeneity and builds a machine learning model to predict the risk of adverse reactions, providing evidence support for the construction of a patient-centered individualized decision-making system.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2000
Start Date
2025-10-01
Completion Date
2028-10-01
Last Updated
2025-09-05
Healthy Volunteers
No
Conditions
Interventions
Interventional therapy
Interventional therapy
Systemic therapy
Targeted Therapy drugs include but are not limited to Lenvatinib, Apatinib, etc. Immunotherapy drugs include but are not limited to Camrelizumab, Tislelizumab
Locations (14)
The Second Affiliated Hospital of Hainan Medical Universsity
Haikou, Hainan, China
Xingtai No.5 Hospital
Xingtai, Hebei, China
Deng zhou People's Hospital
Dengzhou, Henan, China
The Second People's Hospital of Jiaozuo
Jiaozuo, Henan, China
Huai He Hospital of Henan University
Kaifeng, Henan, China
Luo Yang Central Hospital
Luoyang, Henan, China
The First Affiliated Hospital of Henan University of science and Technology
Luoyang, Henan, China
First People's Hospital of Shangqiu
Shangqiu, Henan, China
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
Zhou Kou Central Hospital
Zhoukou, Henan, China
Wuxi No.5 People's Hospital
Wuxi, Jiangsu, China
Jiangxi Provincial People's Hospitail
Nanchang, Jiangxi, China
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
Second People's Hospital of Jiaozuo
Jiaozuo, China