Clinical Research Directory

Inclusion Criteria: * 1 mo. stability in pain management strategies. * 22+ years of age. * Can read and speak English. * Able to participate in strengthening, stretching, range of motion exercise via yoga as determined by study physician. * Chronic Low Back Pain (CLBP): pain in the low back that persists for \>6 months and is of moderate to severe intensity with a score of \>5 on specific items on the BPI demonstrating disability of at least 20% on the Oswestry Disability Index (ODI). Exclusion Criteria: * Contraindications to iTBS/TMS (e.g. epilepsy, psychotic spectrum disorders \[i.e. bipolar, schizophrenia\], history of anoxic brain injury). * Moderate to severe heart disease. * Contraindications to MRI (e.g., claustrophobia, implanted ferromagnetic device such as pacemaker or cardiac defibrillator). * Pain believed to be associated with cardiac or ischemic conditions. * Epilepsy, active seizure disorder, personal history of a seizure or individuals with a family history of epilepsy or seizure in a first degree relative. * Current prescription of psychostimulants (e.g., amphetamines), anticholinergics, tricyclic antidepressants, and antipsychotics or other medications that may increase their risk of having seizures. * Intracranial lesion. * History of ischemic or hemorrhagic stroke. * History of moderate to severe TBI. * History of or current psychosis not due to an external cause (e.g., due to illicit drug use). * Other neurological conditions (e.g., neurodegenerative disorders). * Active suicidal ideation with Columbia Suicide Severity Rating Scale(CSSRS) 3 . * Are pregnant or nursing. * Within 12 weeks of a major surgery/operation.