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Genicular Nerve Block for Knee Pain in the ED
Sponsor: University of Pennsylvania
Summary
Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.
Official title: Ultrasound-Guided Genicular Nerve Block for Knee Pain in the Emergency Department: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
34
Start Date
2025-08-06
Completion Date
2026-09-01
Last Updated
2026-02-12
Healthy Volunteers
No
Conditions
Interventions
Genicular nerve block with bupivacaine and corticosteroids
genicular nerve block with ideal body-weight dosing of bupivacaine 0.5% with 4 mg dexamethasone
Standard of Care
This involves standard of care pain relief for patients who do not receive the genicular nerve block for knee pain, such as acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), and opioids.
Locations (4)
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States
Pennsylvania Presbyterian Medical Center
Philadelphia, Pennsylvania, United States
HUP Cedar
Philadelphia, Pennsylvania, United States