Clinical Research Directory
Browse clinical research sites, groups, and studies.
Acute MI UDMI Staging Diagnosis by High-sensitivity Cardiac Troponin-I
Sponsor: Rohan Dharmakumar
Summary
TROP-MI-STAGE is a multicenter retrospective diagnostic study designed to evaluate the role of high-sensitivity cardiac troponin I (hs-cTnI) in the diagnosis and clinical stage classification of acute myocardial infarction as defined by the stages of myocardial injury in CCS-AMI classification. The study retrospectively analyzes biomarker data from patients diagnosed with AMI across multiple institutions, focusing on whether hs-cTnI levels-measured at specific time points-can reliably identify and stratify patients into AMI clinical stages (Stage 1 to Stage 4). It aims to correlate hs-cTnI kinetics and peak levels with clinical stage, presentation patterns, and outcomes. This trial seeks to offer a biomarker-based alternative to imaging-heavy staging, potentially streamlining early diagnosis and therapeutic triage for AMI patients in varied clinical settings.
Official title: High-Sensitivity Cardiac Troponin I as a Diagnostic Marker for AMI Clinical Stage Classification in Acute Myocardial Infarction: A Retrospective Multicenter Study
Key Details
Gender
All
Age Range
18 Years - 79 Years
Study Type
OBSERVATIONAL
Enrollment
312
Start Date
2023-01-10
Completion Date
2025-09-30
Last Updated
2026-09-16
Healthy Volunteers
No
Conditions
Locations (1)
Medical Imaging Research Institute
Indianapolis, Indiana, United States