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Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches
Sponsor: Emory University
Summary
The goal of this study is to assess the effects of nicotine concentration and its interplay with pH on sensory experience, product appeal, and abuse liability of NPs among young adults NP users. Primary objective is to assess the effect of variation in nicotine concentration in nicotine pouches (NPs) and its interaction effect with pH level on three proximal outcomes of relevance to regulation: (1) sensory experience, (2) product appeal, and (3) abuse liability of NPs.
Key Details
Gender
All
Age Range
21 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
84
Start Date
2026-02-13
Completion Date
2028-01
Last Updated
2026-02-27
Healthy Volunteers
Yes
Conditions
Interventions
Nicotine pouch: Low dose
Nicotine pouch: 3-4 mg
Nicotine pouch: High dose
Nicotine pouch: 6-8 mg
Low pH
Nicotine pouch with low pH level \[\<8.5\]
High pH
Nicotine pouch with high pH level \[\>8.5\]
Locations (1)
Rollins School of Public Health
Atlanta, Georgia, United States