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NOT YET RECRUITING
NCT07166835
NA

Exploring the Cognitive Benefits of a Blackcurrant-Based Supplement in Normobaric Hypoxia

Sponsor: Leeds Beckett University

View on ClinicalTrials.gov

Summary

This study investigates the cognitive effects of Ārepa, a blackcurrant-based drink, under simulated high-altitude conditions (4,500m normobaric hypoxia for \~180 minutes). Using a double-blind, randomised, placebo-controlled crossover design, participants will consume either the nootropic blackcurrant-based drink or a taste-matched placebo. Cognitive testing (\~80 minutes) includes Trail-making, Stroop, N-back, Serial 7s/3s, and RVIP tasks. Physiological measures (heart rate, SpO₂, blood) and biomarkers (MAO-B, BDNF, hsCRP, S100B, Prolactin, C3G, Sarmentosin) will be assessed. Scales will evaluate mood, wellbeing, and perceived effects. The aim is to determine if the nootropic drink can support cognitive function in hypoxic environments.

Official title: The Efficacy of a Blackcurrant-based Nootropic Drink to Support Cognitive Functioning Under Normobaric Simulated High Altitude

Key Details

Gender

MALE

Age Range

18 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

27

Start Date

2025-09-01

Completion Date

2027-10-01

Last Updated

2025-09-10

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Nootropics (ginkgo biloba, nicergoline, piracetam, or others)

Nootropic drink containing Anthrocyanins, L-theanie and Enzogenol

DIETARY_SUPPLEMENT

Placebo

Taste- and appearance-matched placebo beverage without active ingredients.

Locations (1)

Leeds Beckett University

Leeds, United Kingdom