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Exploring the Cognitive Benefits of a Blackcurrant-Based Supplement in Normobaric Hypoxia
Sponsor: Leeds Beckett University
Summary
This study investigates the cognitive effects of Ārepa, a blackcurrant-based drink, under simulated high-altitude conditions (4,500m normobaric hypoxia for \~180 minutes). Using a double-blind, randomised, placebo-controlled crossover design, participants will consume either the nootropic blackcurrant-based drink or a taste-matched placebo. Cognitive testing (\~80 minutes) includes Trail-making, Stroop, N-back, Serial 7s/3s, and RVIP tasks. Physiological measures (heart rate, SpO₂, blood) and biomarkers (MAO-B, BDNF, hsCRP, S100B, Prolactin, C3G, Sarmentosin) will be assessed. Scales will evaluate mood, wellbeing, and perceived effects. The aim is to determine if the nootropic drink can support cognitive function in hypoxic environments.
Official title: The Efficacy of a Blackcurrant-based Nootropic Drink to Support Cognitive Functioning Under Normobaric Simulated High Altitude
Key Details
Gender
MALE
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
27
Start Date
2025-09-01
Completion Date
2027-10-01
Last Updated
2025-09-10
Healthy Volunteers
Yes
Conditions
Interventions
Nootropics (ginkgo biloba, nicergoline, piracetam, or others)
Nootropic drink containing Anthrocyanins, L-theanie and Enzogenol
Placebo
Taste- and appearance-matched placebo beverage without active ingredients.
Locations (1)
Leeds Beckett University
Leeds, United Kingdom