Clinical Research Directory

Inclusion Criteria: * Diagnosis of chronic ocular graft vs. host disease (oGVHD) (ICCGVHD criteria probable or definite) * OSDI score of 22 or higher * NEI corneal staining score (or modified NEI score) of 2 or higher. Exclusion Criteria: * Patients with any open wound on the eyelid. * Patient with any active cornea ulcer, dacryocystitis, hordeolum, filamentary keratitis, uveitis, retinal detachment, uncontrolled glaucoma or other active pathology per PI's discretion. * Patient with a pacemaker or ICD. * Patient currently pregnant or with a potential to be pregnant during the study. * Patient undergoing any ocular surgical procedure (including intravitreal injections) within the past 3 months. * Patient undergoing any systemic surgical procedures within 2 months. * Patient undergoing any non-surgical eyelid procedure such as punctal plugs or punctal cautery within 1 month of study initiation. * Patients on cytotoxic agents, drugs that inhibit peripheral nerve regeneration (i.e. Gabapentin, Nicotine), radiation therapy, or any other therapy per PI's discretion. * Patients undergoing immunosuppression regimen change within 1 month of study initiation and/or during the study period. * Patient who wears contact lens of any kind