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ENROLLING BY INVITATION
NCT07167043

An Explainable Neuroradiologist Artificial Intelligence Assistance System for Brain CT and MRI

Sponsor: Yaou Liu

View on ClinicalTrials.gov

Summary

This clinic trial aims to validate the working performance of radiologists with or without artificial intelligence (AI) diagnostic tool at neurological diseases diagnosis on brain CT/MRI. Routine diagnosis workflow in real clinical scenario including imaging reading, feature interpretation, differential diagnosis, writing initial report and optimizing revised version. And the gold standards of diagnosis are the histopathology references for brain tumors and the discharge diagnosis integrating all the examination results for the other neurological diseases. The performance of AI-assisted tools on diagnosing should be examined in a clinical process with multiple aspects identical to human radiologists' work before being transformed and putted to use. This study hypothesizes that AI models, trained with over 100,000 patient scans, are non-inferior to radiologists in neurological disease diagnosis on brain CT and MRI. For the secondary end-points, we investigate the performance of AI-radiologist collaboration of reasoning-enhanced AI-assisted systems. We hypothesize that, by visualizing the process of imaging interpretation and diagnosis, reasoning-enhanced AI can not only improve working performance of radiologists but also boost their trust in AI tools.

Official title: Reasoning Artificial Intelligence Collaborate With Radiologists in Neurological Disease Interpretation and Diagnosis on CT and MRI

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

30000

Start Date

2025-05-01

Completion Date

2030-12-01

Last Updated

2025-09-11

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

AI-assisted diagnostic systems

Diagnosing neurological diseases on CT/MRI with and without AI-assisted tools

Locations (1)

Beijing Tiantan Hospital

Beijing, China