Clinical Research Directory

Inclusion Criteria: * Age 20-55 years. * Clinical diagnosis of cervicogenic headache according to International Classification of Headache Disorders (ICHD-3) criteria (headache attributed to cervical disorder). Exclusion Criteria: * History of major cervical spine pathology such as fracture, dislocation, congenital malformation, tumor, infection, or inflammatory arthritis (e.g., rheumatoid arthritis, ankylosing spondylitis). * Previous cervical spine surgery or fusion at any level. * Red flag symptoms indicating serious pathology (e.g., progressive neurological deficit, unexplained weight loss, fever, history of cancer). * Systemic or neurological disorders that may affect neck function or headache (e.g., multiple sclerosis, Parkinson's disease). * Severe osteoporosis or metabolic bone disease that contraindicates cervical X-ray imaging. * Vascular disorders such as vertebrobasilar insufficiency or carotid artery disease. * Pregnancy or breastfeeding (due to radiation exposure during cervical radiography). * Unstable psychiatric conditions (e.g., severe depression, psychosis) that may interfere with participation or adherence. * Recent physiotherapy or manual therapy targeting the cervical region within the past 6 weeks, or planned during the study outside the protocol. * Use of botulinum toxin or steroid injections to the neck or head region in the past 6 months. * Contraindications to manual therapy or exercise (e.g., acute cervical disc herniation, severe myelopathy, unstable cardiovascular disease). * Inability to understand study procedures, comply with treatment sessions, or provide informed consent. * Symptoms of migraine, tension-type headache (TTH), or any other headache apart from cervicogenic headache.