Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Effect of a Probiotic Administration as an add-on Treatment in Multiple Sclerosis
Sponsor: Hospital Universitari Vall d'Hebron Research Institute
Summary
It is a randomized, double-blind, placebo-controlled clinical trial whose general objective of this study is to determine the effects of probiotic administration in multiple sclerosis patients. 80 patients with relapsing-remitting multiple sclerosis will be enrolled in the study. Patients will be randomly assigned to receive either a probiotic (n=40) or a placebo (n=40) stratified by type of medication, gender and use of hormonal contraceptive treatment. They will receive a probiotic (Lactibane Iki) or placebo sachet twice a day for six months.
Official title: The Effect of a Probiotic Administration as an add-on Treatment in Multiple Sclerosis: a Randomized, Double-blind, Placebo-controlled Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2025-07-10
Completion Date
2027-12-31
Last Updated
2025-09-23
Healthy Volunteers
No
Conditions
Interventions
Lactibane Iki
Patients will receive a probiotic sachet twice a day for six months. The probiotic, Lactibiane iki (Pileje; Paris, France), is composed of Bifidobacterium lactis LA 304, Lactobacillus acidophilus LA 201, and Lactobacillus salivarius LA 302 and contains 4x10E10 CFU/sachet.
Placebo
Patients will receive a placebo (starch) sachet twice a day for six months.
Locations (1)
Centre d'Esclerosi Mútiple de Catalunya (Cemcat)
Barcelona, Barcelona, Spain