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NOT YET RECRUITING
NCT07168785
EARLY_PHASE1

[18F]-AraG PET Imaging in LA HNSCC

Sponsor: Indiana University

View on ClinicalTrials.gov

Summary

This study will use \[18F\]-AraG PET/CT scans to monitor patients who have been diagnosed with locally advanced Head and Neck Squamous Cell carcinoma (LA-HNSCC), and are planning to undergo standard of care chemoradiotherapy for treatment.

Official title: [18F]-AraG PET Imaging for Enhanced Risk Stratification and Chemoradiotherapy Response Assessment in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

5

Start Date

2025-10-01

Completion Date

2027-10

Last Updated

2025-09-11

Healthy Volunteers

No

Interventions

DRUG

[18F]-AraG radiotracer

\[18F\]-AraG radiotracer, which occurs on the first and sixteenth day of treatment.

DRUG

Chemotherapy

Concurrent chemoradiotherapy (CRT) with weekly doses of cisplatin.

DEVICE

Radiotherapy

Concurrent chemoradiotherapy (CRT) of 70Gy of radiation dose in 33 fractions.

Locations (1)

Indiana University

Indianapolis, Indiana, United States