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Predictors of GON Blockade Success in Migraine
Sponsor: Başakşehir Çam & Sakura City Hospital
Summary
This multicenter, prospective cohort study aims to identify clinical and demographic predictors that influence the success of greater occipital nerve (GON) block in patients with migraine. Patients will be evaluated at baseline, on each injection day, and at one- and three-month follow-ups. Study parameters include demographics, migraine type and duration, comorbidities, headache characteristics, treatment history, and validated outcome measures such as the Numeric Rating Scale (NRS), Headache Impact Test-6 (HIT-6), and Global Rating of Change (GRoC). The goal is to establish predictive factors of treatment success in order to optimize patient selection and contribute robust multicenter evidence to individualized migraine management
Official title: Predictive Factors for the Success of Greater Occipital Nerve Block in Migraine: A Multicenter Prospective Study
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
460
Start Date
2025-09-15
Completion Date
2026-12-01
Last Updated
2025-09-12
Healthy Volunteers
No
Conditions
Interventions
Greater Occipital Nerve (GON) Blockade
The greater occipital nerve block (GONB) will be performed using anatomical landmarks (distal approach). The injection point is located at the medial one-third of the line between the external occipital protuberance and the mastoid process. A 26-gauge insulin needle will be used for the procedure. The block will be administered bilaterally with 0.5% bupivacaine, 1.5 ml per side (total 3 ml). The intervention will be repeated once weekly for a total of four sessions
Locations (1)
Başakşehir Çam and Sakura City Hospital
Istanbul, Turkey (Türkiye)