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WBV Reflex Latency and Mechanical Load
Sponsor: Selim Sezikli
Summary
This study aims to investigate how the magnitude of mechanical loading affects reflex latency patterns induced by whole-body vibration (WBV). WBV can trigger two types of reflexes: the tonic vibration reflex (TVR) and the bone myoregulation reflex (BMR), which may be influenced by load-bearing condition. The study will include healthy adult volunteers aged 20-50 years. Reflex responses will be recorded from the soleus muscle using surface EMG during both WBV. Different conditions of mechanical loading (i.e., standing on one foot, both feet) and vibration frequencies (30-36 Hz) will be tested. The main outcome will be the latency of the reflex responses, which will help distinguish between TVR and BMR activation. The goal is to better understand how mechanical load modifies reflex response timing and to characterize the underlying afferent pathways. This knowledge may contribute to optimizing vibration-based rehabilitation strategies.
Official title: Effect of Mechanical Load Magnitude on Reflex Latency Induced by Whole-Body Vibration: A Latency-Based Evaluation of Bone Myoregulation Reflex and Tonic Vibration Reflex
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-09-02
Completion Date
2025-09-24
Last Updated
2026-10-07
Healthy Volunteers
Yes
Conditions
Interventions
Whole-Body Vibration
Participants will receive whole-body vibration (WBV) at 30-36 Hz under different mechanical loading conditions (e.g., standing on one foot, both feet,). Vibration-induced reflex responses will be recorded from the soleus muscle using surface electromyography. The intervention is designed to evaluate latency differences between tonic vibration reflex (TVR) and bone myoregulation reflex (BMR) under controlled biomechanical scenarios.
Locations (1)
Istanbul Physical Medicine and Rehabilitation Training and Research Hospital
Istanbul, Istanbul, Turkey (Türkiye)