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Assessment of GIT Vasculopathy in SSc and Its Multisystem Correlations
Sponsor: Esraa Moustafa Mohammed
Summary
* Evaluation of splanchnic vasculature, including arterial blood flow using Doppler ultrasound in patients with systemic sclerosis compared to healthy subjects. * Correlation of Doppler findings of splanchnic vessels with GIT manifestations. * Correlation of Doppler findings of splanchnic vessels with macrovascular affection (chest, cardiac, and renal), microvascular involvement (capillaroscopy findings), and autoantibodies (anti-SCL70 antibody and anti-centromere antibody).
Official title: Assessment of Gastrointestinal Vasculopathy in Systemic Sclerosis and Its Multisystem Correlations
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
74
Start Date
2025-10-01
Completion Date
2026-11
Last Updated
2025-09-12
Healthy Volunteers
No
Interventions
Doppler ultra sound
\- Doppler Ultrasound (DUS) To evaluate the abdominal aorta and the 3 main splanchnic vessels: Celiac Trunk (CT) Superior Mesenteric Artery (SMA) Inferior Mesenteric Artery (IMA) An ultrasound examination will be performed after a fasting period of at least 8 hours by a single operator blinded to clinical features. For abdominal vessels, the following parameters were measured: caliber, thickness, echogenicity, peak systolic velocity (PSV), end diastolic velocity (EDV), reverse velocity (RV), mean velocity (MV), resistive index (RI), and pulsatility index (PI).
Locations (1)
Assiut University, Assiut, 71111
Asyut, Egypt