Clinical Research Directory
Browse clinical research sites, groups, and studies.
Pelvic Floor Muscle Training With Aerobic Exercise and Relaxation After Radical Prostatectomy
Sponsor: Hacettepe University
Summary
Post-prostatectomy urinary incontinence (PP-UI) and erectile dysfunction (ED) are common complications after radical prostatectomy, negatively affecting quality of life. Pelvic floor muscle training (PFMT) is widely recommended as the first-line conservative treatment, but recent evidence suggests that multimodal, structured rehabilitation may further improve recovery. This randomized controlled trial will investigate the additional effects of aerobic exercise and relaxation training combined with PFMT in men following nerve-sparing robotic-assisted radical prostatectomy. Forty-eight participants aged 40-65 years, within one year post-surgery, who demonstrate voluntary pelvic floor muscle contraction and sufficient cognitive function (MoCA), will be randomly assigned (1:1) to intervention or control groups. All participants will receive standardized education and a 12-week supervised PFMT program with biofeedback and home-based exercises. The intervention group will additionally perform treadmill-based aerobic exercise three times per week and structured relaxation training once per week. Primary outcomes include urinary symptoms (ICIQ-MLUTS), erectile function (IIEF-15), and prostate cancer-specific quality of life (EPIC). Secondary outcomes include pad test, ICIQ-SF, 6-minute walk test, MoCA, HADS, and adherence. This non-commercial study aims to provide high-quality evidence supporting physiotherapy-based multimodal rehabilitation for improved pelvic health and quality of life in men after prostate cancer surgery.
Official title: Radikal Prostatektomi Sonrasında Aerobik Egzersiz ve Gevşeme Eğitimlerinin Pelvik Taban Kas Eğitimine İlave Etkileri
Key Details
Gender
MALE
Age Range
40 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2025-09-15
Completion Date
2026-09-15
Last Updated
2025-09-15
Healthy Volunteers
No
Interventions
Pelvic Floor Muscle Training
Supervised PFMT with biofeedback, 3 times per week for 12 weeks, plus home exercises.
Aerobic Exercise
Treadmill walking, moderate intensity (Borg 4-6), 60 minutes/session, 3 times per week for 12 weeks.
Relaxation Training
Guided breathing, imagery, and meditation, once weekly for 12 weeks, in addition to home practice.
Patient Education
Standardized education on urinary incontinence, pelvic anatomy, lifestyle modification, and stress management.