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Evaluation of the Effect of Salivary Melatonin Levels on Postoperative Pain and Sleep Quality Following Endodontic Treatments Performed at Different Days and Times
Sponsor: Ataturk University
Summary
This clinical study aims to evaluate the effect of salivary melatonin levels on postoperative pain and sleep quality in patients undergoing root canal treatment at different times of the day. Each participant will receive endodontic treatment on two asymptomatic mandibular molars, one in the morning and the other in the afternoon. Pain intensity and sleep quality will be assessed using standard questionnaires, and salivary melatonin levels will be analyzed.
Official title: Evaluation of the Effect of Salivary Melatonin Levels on Postoperative Pain and Sleep Quality Following Endodontic Treatments Performed at Different Times of Day
Key Details
Gender
All
Age Range
25 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2025-09-01
Completion Date
2026-07-20
Last Updated
2025-09-15
Healthy Volunteers
No
Interventions
root canal treatment
Standardized root canal treatment performed on asymptomatic mandibular molars. Procedures include local anesthesia, rubber dam isolation, access cavity preparation, cleaning and shaping with rotary instruments, irrigation with NaOCl and EDTA, and obturation using a standardized protocol. Saliva samples are collected prior to treatment for melatonin analysis. Postoperative pain and sleep quality are assessed using validated questionnaires.
Locations (1)
Atatürk University Faculty of Dentistry, Department of Endodontics
Erzurum, Turkey (Türkiye)