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RECRUITING
NCT07174609
NA

Scrambler Therapy in Chronic Pancreatitis

Sponsor: Johns Hopkins University

View on ClinicalTrials.gov

Summary

The investigators will enroll adults with chronic pancreatitis who have persistent abdominal pain not relieved by standard treatments. This study will test the feasibility and effectiveness of Scrambler Therapy, a non-invasive FDA-cleared device that delivers "non-pain" electrical signals through the skin to retrain the brain's pain perception. Participants will undergo 5-10 treatment sessions and be followed for 3 months with standardized pain scores and quality-of-life assessments. The goal is to generate pilot data to support larger studies of Scrambler Therapy as a novel option for pancreatic pain.

Official title: A Pilot Study of Scrambler Therapy for Painful Chronic Pancreatitis

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-11-01

Completion Date

2026-12-01

Last Updated

2025-09-16

Healthy Volunteers

No

Interventions

DEVICE

Scrambler Therapy

Adults with chronic pancreatitis and refractory abdominal pain will receive Scrambler Therapy, a non-invasive neuromodulation device. Electrodes are placed near the painful area to deliver "non-pain" signals aimed at reducing pain perception. Participants will complete 5-10 daily treatment sessions, each lasting 30-40 minutes, with pain ratings collected before and after sessions and follow-up assessments over 3 months.

Locations (1)

Johns Hopkins Green Spring Station

Baltimore, Maryland, United States