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Population-Based Analysis of Incidence and Mortality of Septic Shock
Sponsor: Hospital de Granollers
Summary
RADAR-Septic Shock is a population-based observational study in Catalonia (Spain) that will identify all hospital discharges with septic shock between 2018 and 2023 using an audited population-based registry. The project will quantify incidence, describe patient characteristics and resource use, and compare risk-adjusted in-hospital mortality across hospitals to support quality improvement. Cases are defined by ICD-10 codes for septic shock (R65.21) and post-procedural septic shock (T81.12XA). In preliminary cohort counts, \>31,000 episodes were identified across 2018-2023; in 2023 the incidence was \~78 per 100,000 inhabitants with an overall in-hospital mortality of \~33%, higher in hospital-acquired than community-acquired episodes
Official title: Population-Based Analysis of Incidence and Mortality of Septic Shock: The Registry of Administrative Data Automatically Recorded-Septic Shock Project
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
31480
Start Date
2018-01-01
Completion Date
2025-11-30
Last Updated
2025-09-16
Healthy Volunteers
No
Conditions
Interventions
Person-level linkage of the database looking for relationship with septic shock survival and comorbidities, previous intake of medication, and previous dependence on health services.
A descriptive analysis of the baseline demographics, risk factors, health status, comorbidities, frailty, and previous dependence on health services of all patients admitted with septic shock to hospitals in the region will be carried out. The overall data of patients admitted to hospitals will be analysed. The survival data of patients will be compared with their previous individual drug consumption and inhospital survival to septic shock. In addition, drug dependence and dependence on health services of survivors will be studied in comparison with their situation prior to sepsis. The objective is to establish the Registry of Administrative Data Automatically Recorded for Septic Shock (RADAR-Septic Shock), leveraging administrative data to characterize septic shock incidence, describe patient profiles, identify population-specific healthcare needs, and provide benchmark values for performance assessment in Catalonia's public health system.
Locations (1)
Hospital General de Granollers
Granollers, Barcelona, Spain