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Effect of I-PRF After Gingivectomy
Sponsor: Faculty of Dental Medicine for Girls
Summary
The goal of this clinical trial is to evaluate the effect of injectable platelet-rich fibrin application on wound healing following gingivectomy or gingivoplasty. The main question it aims to answer are: Does the injectable platelet-rich fibrin enhance the wound healing after gingivectomy or gingivoplasty ? Participants(who have chronic inflammatory gingival overgrowth) will be divided into two groups : Group I: systemically healthy patients with chronic inflammatory gingival enlargement will be randomly treated with gingivectomy or gingivoplasty alone (control). Group II: systemically healthy patients with chronic inflammatory gingival enlargement will be randomly treated with gingivectomy or gingivoplasty and application of injectable platelet rich fibrin on wound area. The patients will be recalled for follow-up appointments on days 7, 14, and 21.
Official title: Evaluation of The Effect of Injectable Platelet-Rich Fibrin Application on Wound Healing Following Gingivectomy or Gingivoplasty: Randomized Controlled Clinical Study
Key Details
Gender
All
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-10
Completion Date
2026-05
Last Updated
2025-09-16
Healthy Volunteers
Yes
Interventions
application of injectable platelet-rich fibrin on the wound area .
Injectable platelet-rich fibrin will be prepared using low speed centrifugation technique, after centrifugation, the I-PRF in the upper part of the tube will be collected via an injector and will be transferred to a metal godet. It will be left for 15-20 min for polymerization of the I-PRF ,Then the polymerized I-PRF will be applied to the secondary wound of test area.
Locations (1)
Out-Patient Clinic of Oral Medicine, Periodontology, Oral Diagnosis and Radiology department, Faculty of Dental Medicine for Girls, Al-Azhar University.
Cairo, Egypt