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Role of Metformin in Posterior Capsule Opacification
Sponsor: Vienna Institute for Research in Ocular Surgery
Summary
Determination of concentrations of systemically applied metformin in human lens capsule and its ability to lower the proliferation rate of human lens epithelial cells in vitro.
Official title: Lens Epithelial Cell Proliferation in Patients Suffering From Diabetes and Treated With Metformin in Vitro: a Pilot Study
Key Details
Gender
All
Age Range
21 Years - 105 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2022-10-12
Completion Date
2025-10-01
Last Updated
2025-09-16
Healthy Volunteers
No
Conditions
Interventions
Blood and lens capsule samples for PK testing
Blood samples and lens capsule tissue will be collected from patients for PK testing
Locations (1)
Vienna Institute for Research in Ocular Surgery (VIROS)
Vienna, Austria