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Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.
Sponsor: Pakistan Institute of Medical Sciences
Summary
In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.
Official title: Comparing the Antiplaque Efficacy of Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients-A Triple Blind Randomised Controlled Trial.
Key Details
Gender
All
Age Range
16 Years - 30 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-11
Completion Date
2027-12
Last Updated
2025-09-25
Healthy Volunteers
Yes
Interventions
Fluoride varnish
Group A will receive conventional fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.
Novel titania nanoparticle infused fluoride varnish
Group B will receive topical application of titania nanoparticle infused fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.
Locations (1)
Pakistan Institute of Medical Sciences
Islamabad, Pakistan