Clinical Research Directory

Inclusion Criteria: * Age over 18 years; * Patients with clinical indication to coronary angiography undergoing intra-procedural OCT regardless of the clinical syndrome; * Patients with at least one end-procedural OCT assessment with a sufficient acquisition length to address the whole length of plaque or stented segments plus the proximal and distal reference segments; * Patient has been informed of the nature of the study, agrees to its provisions, and has provided written informed consent as approved by the Ethical Committee of the respective clinical site. Exclusion Criteria: * Female with childbearing potential or lactating; * Acute or chronic renal dysfunction (defined as creatinine greater than 2.0 mg/dl and/or glomerular filtration rate \<30 ml/min); * Advanced heart failure (NYHA III-IV); * Previous heart transplantation; * Co-morbidities that could interfere with completion of study procedures, or life expectancy less than 1 year; * Participating in another investigational drug or device trial that has not completed the primary endpoint or would interfere with the endpoints of this study; * Heavily calcified lesion or tortuous vessel which cannot be successfully imaged by OCT; * Lesion located at the coronary ostium or in angulated (\>70°), sharp take-off vessel;