Clinical Research Directory

Inclusion Criteria: * Clinical diagnosis of mild skin barrier dysfunction, including: * Mild to moderate atopic dermatitis, defined as SCORAD ≤ 50, and/or not currently requiring topical corticosteroids or immunomodulators. * Mild to moderate chronic plaque psoriasis, defined as total body surface area (BSA) involved: ≤3% to 10%. * Contact dermatitis * Seasonal xerosis or clinically evident skin dryness * Symmetrical or bilateral test areas available (volar forearm) * Willing and able to provide informed consent and adhere to study procedures Exclusion Criteria: * Failure to meet any of the above inclusion criteria * Severe atopic dermatitis or psoriasis requiring systemic or high-potency topical treatment * Use of corticosteroids, calcineurin inhibitors, biologics, or phototherapy within 2 weeks * Open wounds or evidence of secondary infection at test sites * Pregnant or breastfeeding women * Multiple nevi, tattoos, dense body hair in the test areas * Debilitated or immunocompromised subjects * Known or suspected hypersensitivity to the interventional product (or its ingredients) or petrolatum * Refusal or failure to comply with the schedule of visits at the test site.