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RECRUITING
NCT07186127

Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications

Sponsor: Bagcilar Training and Research Hospital

View on ClinicalTrials.gov

Summary

Study Description (For Patients, Families, and Healthcare Providers) Purpose: The aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for whom this treatment is relatively contraindicated. Background: Methotrexate is a medication commonly used in the treatment of ectopic pregnancy (a pregnancy that occurs outside the uterus, usually in the fallopian tube). However, in certain conditions - such as kidney or liver dysfunction - methotrexate use may carry increased risks. These situations are known as relative contraindications. This study will retrospectively examine treatment outcomes in this specific patient population. Method: The study will analyze medical records of patients who were previously treated with methotrexate for ectopic pregnancy. No new interventions will be performed. The analysis will be based solely on existing clinical data. Why Is This Important? The findings of this study may help us better understand the safety limits of methotrexate therapy and guide healthcare providers in managing similar cases in the future.

Official title: A Retrospective Evaluation of the Effectiveness of Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications

Key Details

Gender

FEMALE

Age Range

18 Years - 48 Years

Study Type

OBSERVATIONAL

Enrollment

230

Start Date

2025-05-01

Completion Date

2026-05-01

Last Updated

2025-09-22

Healthy Volunteers

No

Interventions

DRUG

Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond

MTX medical treatment Laparoscopic salpingectomy Laparoscopic salpingostomy

Locations (1)

University of Health Sciences, Training and Research Hospital

Istanbul, Türkiye, Turkey (Türkiye)