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Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
Sponsor: Bagcilar Training and Research Hospital
Summary
Study Description (For Patients, Families, and Healthcare Providers) Purpose: The aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for whom this treatment is relatively contraindicated. Background: Methotrexate is a medication commonly used in the treatment of ectopic pregnancy (a pregnancy that occurs outside the uterus, usually in the fallopian tube). However, in certain conditions - such as kidney or liver dysfunction - methotrexate use may carry increased risks. These situations are known as relative contraindications. This study will retrospectively examine treatment outcomes in this specific patient population. Method: The study will analyze medical records of patients who were previously treated with methotrexate for ectopic pregnancy. No new interventions will be performed. The analysis will be based solely on existing clinical data. Why Is This Important? The findings of this study may help us better understand the safety limits of methotrexate therapy and guide healthcare providers in managing similar cases in the future.
Official title: A Retrospective Evaluation of the Effectiveness of Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
Key Details
Gender
FEMALE
Age Range
18 Years - 48 Years
Study Type
OBSERVATIONAL
Enrollment
230
Start Date
2025-05-01
Completion Date
2026-05-01
Last Updated
2025-09-22
Healthy Volunteers
No
Conditions
Interventions
Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond
MTX medical treatment Laparoscopic salpingectomy Laparoscopic salpingostomy
Locations (1)
University of Health Sciences, Training and Research Hospital
Istanbul, Türkiye, Turkey (Türkiye)